The ultrasonic Studies in liquids are great use in understanding the nature and strength of molecular interactions. The ultrasonic studies of biological materials in aqueous medium are ionized & can act as knowledge of the acid- base properties of proteins. Lysine is a necessary building block for all protein in the body. Lysine plays a major role in calcium absorption; building muscle protein; recovering from surgery or sports injuries; and the body's production of hormones, enzymes, and antibodies. Adenosine plays an important role in biochemical processes, such as energy transfer - as adenosine triphosphate (ATP) and adenosine diphosphate (ADP) & as well as in signal transductions cyclic adenosine monophosphate. Present paper represents the nonlinear variation of ultrasonic and thermo acoustical parameters indicates the overlap of the hydration leads to increased hydrogen bonding interaction between Lysine and Adenosine molecules. This increase in hydrogen bonding with increase in lysine concentration as solvent is reflected in increased by hypochromacity thus indicating stronger solute-solvent interaction with higher concentration. Therefore this study of molecular interaction in between lysine, adenosine and water may provide significant information about compatibility of water and biomaterials.
