Background: The rise in population ageing has led to an increase in neurodegenerative diseases and dementia such
as Alzheimer’s Disease (AD). Alterations in cognitive processes occur underpinning memory, attention, perception and
problem-solving processes [1]. AD affects approximately 50 million people and is more prevalent in Western Europe
rather than Asia and Africa [2]. It remains a complex disease with environmental and genetic factors accounting for its
pathogenesis. It is manifested either sporadically (95%) or hereditary (5%) with gene mutations in the Amyloid Precursor
Protein (APP) or presenilin genes (PS1, PS2) [3].
