Experiments show that the formation of adhesions begins with initial development of exudative purulent inflammation followed by productive inflammation with active proliferation of macrophage cellular elements. Neutrophilic infiltration of granulation tissue is long-termed, with a tendency to secondary suppuration. Transformation of granulation tissue into fibrous tissue occurs from day 14 to 30. On the 60th day, volume adhesions accompanied by hyalinosis, subpleuralpleurogenic pneumosclerosis with a tendency to pulmonary sclerosis develop.
