The aim of this study is to perform comparative study of efficiency of topical application of decamethoxine and antiinfective drugs in patients with nonspecific pleural empyema. This study is based on the analysis of treatment outcomes in 51 patients with acute pleural empyema who received medical treatment in thoracic department of V.T. Zaytsev Institute of General and Emergency Surgery of NAMS of Ukraine from 2010 to 2015 years. Absence of displacement of causative agents from pleural discharge in patients of main group was observed in 8 – 10 days while in control group this was in 13 – 15 days. Application of proposed pleural cavity sanitation procedure allowed to reduce length of stay in hospital for patients of main group in a mean of 7.2 ± 1.3 bed days.
