Reaction of isonicotinohydrazide with different aromatic aldehydes under the microwave
irradiation gives Schiff’s bases. These Schiff’s bases were converted into 1, 3, 4-oxadiazole
derivatives by treating with acetic anhydride under the microwave irradiation. The structures of
the compounds were confirmed by elemental analysis, IR, 1HNMR and Mass spectral data’s .The
synthesized compounds were screened for antimicrobial, analgesic and anti-inflammatory
activities.
