The aim of this study was to determine the effects of maternal size on egg production in saline-tolerant tilapia O. mossambicus. Female broodstocks were taken from the ponds, kept in concrete tanks and classified into size groups: small-sized (20.1-26 g), medium-sized (26.1 – 32.0 g) and large-sized group (32.1 – 38.0 g) and allowed to be paired with male broodstocks in a ratio of 3 females to 1 male. They were fed a commercial diet containing 30% crude protein. Fecundity, relative fecundity, weight of gonads and Gonadosomatic Index (GSI) were determined. Fecundity of O. mossambicus were in the range of values reported by other investigators. Fecundity and relative fecundity of saline-tolerant O. mossambicus were influenced by the maternal body size; the relationships of fecundity with total body weight and with gonad weight were linearly correlated.