Traditional system of medicine consists of large number of plant with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive molecules. Luffa cylindrica found all over the world. It is commonly known as ‘tori’ and has been recognized in different traditional system of medicines for the treatment of varied diseases of human being. The phytoconstituents present in it mainly belong to the category of flavonoids. Different part of this plant are traditionally claimed to be used for the treatment of broad spectrum of ailment including snake bites, convulsions, cramps, tetanus, emetic, cathartic, dropsy, nephritis, chronic bronchitis, asthma, sinusitis and fever to be list a few.