The purpose of the present study was to compare the leg explosive power and handgrip strength of Indian college level men physical education and non-physical education students and also find out the relationship with body composition variables to leg explosive power and handgrip strength. A total of 500 (physical education- 250 & nonphysical education- 250) college level male students, aged 18-25 years (mean 22.29 ± 2.21) were selected purposively selected as the samples of the study. Sargent vertical jump test and a standard adjustable digital handgrip dynamometer were used for measuring leg explosive power and handgrip strength respectively. Anthropometric measurements were taken for estimating % body fat, % skeletal muscle mass, lean body mass and body surface area of the selected subjects. The findings of the present study showing that physical education students have higher mean values in leg explosive power (P ≤ 0.01) and handgrip strength (P ≤ 0.01) than nonphysical education students. Leg explosive power had significantly positive correlation (P≤0.01) with % skeletal muscle mass and lean body mass and significantly negative correlation (P≤0.01) with rest of the body composition variables irrespective of physical education and non-physical education students. Handgrip strength had significantly positive correlations (P≤0.01) with all the body composition variables irrespective of physical education and non-physical education students. It may be concluded that physical activity has strong positive relationship with leg explosive power and handgrip strength.