From the air dried seed kernels of Mangifera indica Linn., three known secondary metabolites: Methyl gallate (1), Gallic acid (2) and 1,2,3,4,6- Penta-O-galloyl-β-D-glucose (3) were isolated from active fraction of folklore medicinal plant. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with known compounds. The methanolic extract, its fractions and isolated compounds were examined for in-vitro elastase inhibition activity and found that methanolic extract and ethyl acetate fraction showed an excellent activity and also two of the compounds showed good synergistic activity.
