simple, selective, accurate isocratic high performance liquid chromatographic (HPLC) method was developed and validated for the analysis of Elvitegravir (EVG) in pure and in dosage forms. Chromatographic separation was achieved isocratically on a Thermo Scientific Hypersil BDS C18 column (150 mm x 4.6 mm I.D., 5 μm particle size) utilizing a mobile phase of phosphate buffer ( pH =5.0) and acetonitrile (ACN) in the ratio of 60:40 %v/v at a flow rate of 1.0ml/min with UV detection at 265nm. Calibration curve was linear over the concentration range of 15μg/ml - 90μg/ml of EVG. The drug was subjected to stress conditions of hydrolysis (acid and base), oxidation, photolysis and thermal degradation as per International Conference on Harmonization (ICH) prescribed stress conditions to show the stability-indicating power of the method. The retention time of EVG was 4.717min . The developed RP-HPLC method was validated in terms of accuracy, precision, linearity, limit of detection (LOD) and limit of quantification (LOQ). This paper is aimed for developing and validating an RP-HPLC method, being simple, accurate and selective, and the proposed method can be used for the estimation of EVG drug in dosage form.