The study was designed to examine the In vitro antioxidant activities of ethanol extract of whole plant of waltheria indica (Linn.). The antioxidant activity evaluated by DPPH (2, 2-diphenyl -1- picryl hydrazyl) method, superoxide anion scavenging and iron chelating activity With reference standard content Rutin, Quercetin, EDTA respectively. DPPH radical scavenging activity of ethanolic extract and reference standard Rutin IC50 values was found to be 1020 mg/ml and 480 mg/ml, superoxide anion scavenging activity of ethanolic extract and reference standard Quercetin IC50 values was found to be 410 mg/ml and 60 mg/ml and iron chelating activity of ethanolic extract and reference standard EDTA IC50 values was found to be 420 mg/ml and 65 mg/ml respectively. The above result of possess good an antioxidant activity when compare to the above all standard.
