The extracts of Uvaria chamae, Cassia arereh, Aristolochia albida, Pseudocedrella kotchyii, Tamarindus indica and Nebouldia laevis were evaluated for secondary metabolites and antimicrobial activity. Phytochemical investigations revealed the presence of alkaloids flavonoids, steroids, glycosides, cardiac glycosides, tannins, saponins and anthraquinones. Brine shrimp lethality tests carried out indicate high activities for methanol and ethyl acetate extracts of the plants (BST LC50 3.4 – 114.4 μg/cm3) The extracts exhibited various levels of activities against Escherichia coli, Streptococcus pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Aspergillus flavus and Aspergillus niger.
