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Invitro anthelmintic activity of fresh juice and ethanolic extract of Garcinia cambogia (Clusiaceae) | Abstract
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Annals of Biological Research

Abstract

Invitro anthelmintic activity of fresh juice and ethanolic extract of Garcinia cambogia (Clusiaceae)

Author(s): Veeradass Rajendran*, Rathinambal V and Gopal V

The crude ethanolic extract and fresh juice from the fruits of Garcinia cambogia, were evaluated for their anthelmintic activity using adult earth worms. Five concentrations viz 5, 10,15,20,25 mg/ml of ethanolic extract and 10,20,30,40 and 50 μg/ml of fresh juice of G. cambogia were studied for anthelmintic activity, which involved the determination of colour change, time of paralysis and time of death of worms. Both the ethanolic extract and fresh juice exhibited a dosedependent inhibition of spontaneous mobility (paralysis) and evoked response to pin-prick and death with higher doses (25mg/ml of alcoholic extract and 50ml of fresh juice of G.cambogia), Piperazine citrate in 15mg/ml concentration was included as standard reference and normal saline as control . The results shows that both the extract and fresh juice posses anthelmintic activity.