IBS is one of the most common gastrointestinal disorders which is more related to socio-psychological factors than illnesses such as colitis.in this study, the relationship of psychological factors with IBS has been Investigated in patients reefing to gastrointestinal in Ilam city in 2014. This study is a case-witness study, in which90 people of those referring to gastrointestinal clinics including 45suffering from IBS and 45healthy were Investigated. All necessary in formation in clouding: age, gender, marital condition, education, job, drug and cigarette use were collected. The Results showed significant mean difference among body. Depression social functional and psychological healthy factors in people suffering from IBS compared to healthy people (P<0.001). The Results showed larger degrees of social function, agitation depression and body factors in patients suffering from IBS. So curing psychological problems along with the illness is recommended.