Nigeria is one of the countries with the highest number of people infected with Schistosomiasis and for the control and or eradication of this disease, an integrated approach involving chemotherapy, vector control and health education is imperative. In case of vector control, the use of plants available locally in the endemic areas is recommended. The family Sapindaceae consists of about 2000 species in about 150 genera. They are mostly trees and shrubs but rarely herbs and most are used in ethno-medicine as fish poison. A total of 11 extracts from 8 plants in the family Sapindaceae were screened for mollusccidal activity against Biomphalaria glabrata snail, one of the vector of schisosomiasis, The results showed that only the stem bark of Zanha goluogensis gives 100% mortality at 150ppm with LC50 60ppmof which is above the level recommended by the World Health Organization
