The present study was carried out to assess the effect of different intensity levels of single-session resistance exercise on the serum levels of lipid peroxidation and muscle damage markers in sedentary males. Fifty healthy sedentary males were randomly divided into four groups, one control (n=10) and three treatment groups tested under low (n=14), moderate (n=13) and high (n=13 exercise intensities. The six repetition maximum test (6RM) was used to estimate current one repetition maximum (1RM) score for the back squat, bench press, lat pull-down, stand calf raise, arm curl and leg press. Following circuit resistance exercise using loads of 40%, 60% and 80% of 1RM. The amount of malondialdehyde (MDA) and creatine kinase (CK) were measured. The results revealed a significant effect of the intensity levels of resistance exercise on the serum levels of MDA (P = 0.001) and CK (P = 0.001) posttest when compared with the controls. The amount of MDA and MDA was shown to be increased by increasing the intensity level of the exercise, suggesting that resistance exercise performed at low intensity was most suitable for helpful sedentary males prevent lipid peroxidation and muscle damage.
