This experiment was carried out to determine effect of dietary with deferent level of poly germanderon performance, egg quality, blood biochemical of laying hens. This study was carried out with 300of Hy- line (W36) hens in 4 treatment groups,3 repetitions and 25 hens for each group. The groups were F1) Control group, F2, F3, and F4 with 100, 150, and 200 ppm poly germander extract respectively. Dietary supplementation of various levels of poly germander extract caused significant changes on performance and egg quality. The highest level of food intakeand production percentwere seen in F4. Also the best result for Yolk weight and shell thickness was in groups 4. The serum total cholesterol and Triglycerides concentration were significantly reduced in groups of 4 and 5 compared to the control group (P<0.05). But the concentration of serum LDL, HDL and glucose were not significantly reduced in groups compared to the control group.