Plants are being extensively explored for harbouring medicinal properties. They are one of the major sources for drug discovery and development. Nature had been known as stockyard of medicinal agents since the time immemorial. Herbal products are extensively perceived as safe because they are natural having less or no side effects. In this aspect, Hemigraphis alternata (Burm.f.) T. Anderson was shown to possess many medicinal properties. The in vitro thrombolytic activity of H. alternata leaf extract was evaluated. In the hot and cold water leaf extracts of H. alternata the in vitro thrombolytic activity was recorded as 96±0.70% and 80±0.97%, respectively. Highest thrombolytic activity was found to be preserved by the hot water extract which could be recommended for curing human ailments.
