Damage to cells caused by free radicals is believed to play a central role in the aging process and in disease progression. Many aromatic, medicinal and spice plants contain compounds that possess confirmed strong antioxidative components. The medicinal value of plants have assumed an important dimension in the past few decades owing largely due to the discovery as a rich source of antioxidants that combat oxidative stress through their redox active secondary metabolites and the rising concerns about the side effects of synthetic drugs. These factors have inspired the widespread screening of plants for possible antioxidant properties. Scientific interests in medicinal plants are emerging as plants are invaluable sources of new drugs and plant based antioxidants are preferred to the synthetic ones because of safety concerns. To evaluate antioxidant activity of different solvent fractions obtained from the leaves of Prosopis cineraria. Scavenging ability of the extracts for radicals like DPPH, ABTS, hydroxyl, superoxide, nitric oxide and hydrogen peroxide were performed to determine the potential of the extracts. All six fractions showed to have scavenging activity. The ethyl acetate and methanolic extracts showed to have maximum scavenging activity
