Streptomyces sp. is a promising source for secondary metabolites exhibiting diverse biological activities. The present study reports the antimycotic activity against Candida albicans ATCC 24433 by soil isolate Streptomyces sp. M7. Antimycotic activity against Candida albicans ATCC 24433 was tested by agar well diffusion method on sabouraud dextrose agar plate with the zone of inhibition 29 mm ± 0.5 mm. Isolate was grown in starch casein nitrate broth at 30°C on a rotary shaker at 200 rpm. The antimycotic activity was determined after 5 days of incubation. Isolate was characterized as Streptomyces chromofuscus based on morphological and biochemical characterization and using PIB-Win identification software with a score 1.0.