Der Pharmacia Lettre
Abstract
Author(s): Yanala Suresh Reddy*, Anitha G., M. Nagulu, M. Rajavardhan Reddy, P. Hari Prasad,
M. Jagath Sweth, V. Rajesh Kumar, G. P. Chandra Shekar Reddy
Traditional knowledge and ethno-botanical use of plants have been widely acknowledged all over the world. In the
present scenario, emergence of multiple drug resistance to human pathogenic organisms, this has necessitated a
search for new antimicrobial substances from other sources including plants. Justicia gendarussa a traditional
medicinal liana, used by rural peoples, villagers and tribals residing in different parts of Maharashtra, Tamil Nadu
and Kerala, to treat various ailments. The Muthuvans, Chinnar tribe of Idukki district, Kerala is using stem bark of
this plant as a remedy for inflamation. The study was carried out to ascertain the antibacterial properties present in
different extracts of dried leaves of Justicia gendarussa The Antibacterial testing of leaf extract Justicia gendarussa
was evaluated by Agar well diffusion method using gram positive bacteria like Staphylococus aureus, Bacillus
subtilius, gram negative bacteria like Escherichia coli, Klebseilia pneumoniae. Amongst the test extracts, the results
suggested that, Ethyl acetate, Ethanol extracts of leaf showed significant antibacterial activity compared with
standard drug.
