Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus. Many genes have been identified for its pathogenesis. SORD is one of the candidate gene involved in the development of diabetic retinopathy. An in silico technique was initiated to characterize the properties and structure of the protein. The SORD protein analyzed in the study showed that this is a stable protein and belong to the medium chain dehydrogenase / reductase protein family (MDR). The secondary structure prediction of the protein revealed that the presence of maximum number of random coils as its secondary structure elements. The 3D structure was modelled using Swiss model workspace and the structure was validated. The present study gave an outlook on SORD protein and further research was carried out in preventing the pathogenesis of disease.
