Different species of plants serve the health needs of large number of human being. The present study of phytochemical analysis of aerial parts of Cissus quadrangularis L. Variant-I of two different samples was extracted with aqueous alcohol (50% ethanol) and analysed using GC-MS. Nearly thirty bioactive chemical compounds were identified in both extracts. Predominantly acid derivatives, fatty acid, fatty acid ester, alcoholic compounds and hydrocarbons were present. This analysis revealed that the existence of n-hexadecanoic acid, ethan-1,1-diethoxy, 9,12,15-octadecatrienoic acid-methyl ester(Z,Z,Z) as major constituents. These different active phytochemicals have been found to possess a wide range of biological applications.
