This study was designed to investigation the chronic treatment of Teucrium polium L. Capitatum on serum glucose, and lipid profiles (serum total cholesterol, triglycerides), and plasma Na+, K+, urea concentrations. Ethanolic extract of Teucrium polium L. Capitatum, was administered orally (20-50 mg/kg body weight) in laboratory rats for 30 days. The different doses of Teucrium polium L. Capitatum on serum lipid profile viz. total cholesterol and triglycerides, glucose, and serum Na+, K+, urea concentrations were studied and compared against respective control groups. Serum cholesterol and triglyceride values decreased significantly (p<0.01) in the test groups, but serum glucose values were unaffected by Teucrium polium L. treatment compared to non-treated control animals. According to the experimental findings, the decreased lipids clearly showed the antihyperlipidemic effect of Teucrium polium L. Capitatum apart from its antidiabetic effect.