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Green chemistry approach for synthesis of 5-arylidine barbituric acid derivatives by hydrotrope induced Knovenagel condensation in aqueous medium | Abstract
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Abstract

Green chemistry approach for synthesis of 5-arylidine barbituric acid derivatives by hydrotrope induced Knovenagel condensation in aqueous medium

Author(s): Santosh Kamble, Gajanan Rashinkar, Arjun Kumbhar, Kavita Mote, Rajashri Salunkhe

An efficient Knovenagel condensation of babituric acid with different aromatic aldehyde in aqueous hydrotropic solution affording the corresponding 5-arylidine barbituric acid derivatives in very short time of reaction with high yield and purity.