Antioxidant activities of ethyl acetate extract from Limonium bonduelli and its constituents : eriodictyol, luteolin, apigenin and 4-hydroxy-3-methoxy benzoic acid , were studied in vitro. The phenolic and flavonoid contents were determined and inhibition of malondialdehyde formation and the scavenging of DPPH were assayed. The extract and pure flavonoids, eriodictyol and luteolin showed a high antioxidant effect, especially scavenging of DPPH anions and inhibition of lipid peroxidation compared to vitamin C. The total content of phenolic compounds and total flavonoids content of ethyl acetate extract of Limonium bonduelli were 353 μg of gallic acid equivalents/mg extract and 170.5 μg of quercetin equivalents/mg extract respectively. eriodictyol, luteolin, apigenin and 4-hydroxy- 3-methoxy benzoic acid are described for the first time for Limonium Bonduelli.