A field and a laboratory experiments were conducted in 2009 to determine the effect of irrigation treatments on yield, yield components and seed germination of foxtail millet (Setaria italica). Conventional furrow irrigation (M1) and alternate furrow irrigation (M2) methods and different deficit irrigation levels including 100, 85, 70 and 55% of crop water requirement (V1, V2, V3 and V4) made the treatments. Seeds of the field experiment were used for the laboratory experiment. In the laboratory experiment, germination traits of seed produced from maternal plant under irrigation treatments were tested. Results showed that irrigation treatments had a significant effect on panicle number, panicle length, panicle weight, seed yield and biological yield. M1V1 had higher seed yield than M2V1, M2V3, M1V4 and M2V4. Irrigation treatments did not have any significant effect on seed germination traits. Overall, it is concluded that water stress and irrigation methods had minor effect on seed yield and yield components. It was found that foxtail millet was drought-resistant