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Formulation of Vitamin D3 + Calcium tablets and evaluation of Physical and chemical Properties | Abstract
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Abstract

Formulation of Vitamin D3 + Calcium tablets and evaluation of Physical and chemical Properties

Author(s): Amit Sarker, Md. Mahmudul Hasan, Md. Iftekhar Hussain, Riazul Haque Tuhin, Taslima Begum and Prozzal Roy

The aim of this investigation was to develop Vitamin D3 and Calcium tablets by wet granulation method using excipients and to compare the tablet properties with BP specification. The blend was compressed on a single punch machine, tablets were subjected to various tests (weight variation, diameter and thickness, hardness, disintegration and assay of the drug) and the results were also in compliance with the official specifications. All the physical properties studied indicated that all excipients are good pharmaceutical excipients in tablets. The objective of this work was to present Vitamin D3 in granular and tablet form with improved dispersability, to minimize the complexity of formulations and to make cost effective product.