Helicobacter pylori is commonly associated with peptic ulcer cases as it, infects at least half of the world's population. H. pylori infection is typically acquired in childhood and persists chronically, probably continuing in the stomach throughout life. This research is aimed at comparing the efficacy of the faecal antigen tests with serology in detecting H. pylori in suspected peptic ulcer patients. Three hundred and seventy nine stool samples and equal number of blood samples were tested for antigens and antibodies to H. pylori respectively from208 males and 171 females of between 7- 57 years of age. Samples from one hundred and twenty six (33.2%) and 141 (37.2%) study participants were reactive to rapid faecal antigen and serology tests respectively. It is concluded that faecal antigen and serology for H. pylori are both effective diagnostic tools of the infection, and either one could be useful in early detection of the disease.