The present studies are to review the Psidium guajava Linn leaves and bark is used for anti-oxidant activity. And compounds in tannin like poly-phenolic are served as a free radical scavenging activity in many bacterial associated diseases. Guva is most popular plant in India and it is freely available in all over India. As it is having high in medicinal values we choose these for our research. Methods: Extraction of tannins from Psidium guajava Linn leaves and barks. Find out the anti-oxidant activity.