The present study was conducted to evaluate the hepatoprotective activity of ethanolic extract of Ficus benjamina Linn. against CCl4 induced liver damage in rats. The ethanolic extract of Ficus benjamina Linn. (250 and 500mg/kg) and isolated compounds (500mg/kg) was administered orally to the animals with hepatotoxicity induced by CCl4 (1.5 gm/kg). Silymarin (100mg/kg) was given as reference standard. All the test drugs were administered orally by suspending in liquid paraffin solution. The plant extract and both isolated compound was effective in protecting the liver against the injury induced by CCl4 in rats. This was evident from significant reduction in serum enzymes SGPT, SGOT, ALP, Serum bilirubin and liver weight. It was concluded from the result that the ethanolic extract of Ficus benjamina possesses hepatoprotective activity against CCl4 induced hepatotoxicity in rats.
