Der Pharmacia Lettre

Abstract

Efficient method for the synthesis of 3-pyridyl methanol from nicotinic acid using sodium borohydride-methanol system

Author(s): Madhukar Deshmukh, Sangram Patil, Kaushik Banerjee, Dasharath Oulkar and Chetan Shripanavar

Nicotinic acid is esterifies by using methanol as a solvent in catalytic amount of concentrated Sulfuric acid, to get methylnicotinate, which was subsequently reduced with NaBH4-MeOH system to 3-pyridyl methanol in high yields.

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