The aim of present study was to evaluate the influence of probiotic, prebiotic and synbiotic on performance values and blood enzymes of Japanese Quails. Total of 192 one-day old Japanese quail chicks were randomly assigned in 4 treatments and 4 replicates. The experimental diets consisted of a basal diet without additive (Control), 0.2 g/kg probiotic (Protexin®), 1.6 g/kg prebiotic (Fermacto®) and 1.0 g/kg synbiotic (Protexin®+ Fermacto®) added to the basal diet. Birds fed synbiotic elevated body weight compared to other groups (P<0.05). Feed intake of birds fed synbiotic and prebiotic were higher than control and probiotic fed groups (P<0.05). Birds fed synbiotic exhibited a better feed conversion ratio (3.09) compared to probiotic fed (3.19) and control groups (3.14) (P<0.05). The males fed additives showed decrease in liver weight (P<0.05). Females fed prebiotic and synbiotic showed decrease in liver weight compared to control group (P<0.05). The relative weight of heart was decreased in the males fed prebiotic and synbiotic compared to control group (P<0.05). The females fed probiotic showed increase in heart weight (P<0.05). The activity of ALP in females depressed by prebiotic consumption (P<0.05). In males fed probiotic or synbiotic ALT activity was depressed (P<0.05). LDH activity in males fed synbiotic depressed (P<0.05). In both gender CPK activity was higher in prebiotic and synbiotic feeding groups (P<0.05). Results indicated that using synbiotics (Protexin®+ Fermacto®) has positive effects on performance and normal activity of enzymes. Prebiotic (Fermacto®) has positive effects on performance and reduction weigh of heart and liver in Japanese quails.
