The purpose of the study was to determine the effect of Mentha piperita inhalation on VO2max and reaction timeÃ?Ë?Ã?Å? Tabriz of man elite karate-do of with average age(20.30± 6.49) average weight ( 77± 2.90 kg) Average height (175.25± 1.94cm). 20 male athletes voluntarily participated in the study. Regarding the Maximum amount of consumed oxygen obtained from Bruce test results participants divided into two groups of 10(Experimental and control). Participants of experimental group inhaled the peppermint (pumped in experiment rooming which the 2 ml of pumped peppermint mixed with white alcohol in area of 35m2, temperature of 24 c and humidity of 40-55%) and used on reaction time, of male athletes test and then two drops of peppermint odor for Bruce test. Similar tests performed on control group too, but the only difference was that peppermint replaced with white alcohol. To determine the significance of the findings the statically analysis method of T- test was used. Results suggest that there is a meaningful relationship between the administration of Mentha Piperita with aerobic performance (p≤0/002) and reaction time (p≤0/05).