The purpose of this study was to determine the effect of pre-exercise carbohydrate meals with high glycemic index (HGI) or low glycemic index (LGI) on high sensitive C-reactive protein concentrations (hs-CRP) following subsequent endurance exercise. 12 male subjects (age 24.8 ± 0.35 yrs, body mass 76.1 ± 3.5 kg, height 1.77 ± 0.02 m, body fat percentage 11.1 ± 3.23, VO2max 51.18 ± 0.65 mL·kg-1·min-1; mean ± S.E.M.) performed two 90-min runs on a treadmill at 70% VO2max two hours after ingesting a HGI or LGI meal. Each isocaloric test meal contained 1 g·kg-1 body mass of carbohydrate and the glycemic index values were 94 and 40, respectively. Trials were separated by at least 7 days in counterbalanced order. Results were analyzed using a two-factor (trial × time) repeated measures ANOVA with post hoc (Bonferoni) comparison as appropriate.Laboratory data showed that although hs- CRP levels increased insignificantly immediately after exercise compared to pre exercise levels in both HGI and LGI, a slight increase in hs-CRP1hour after exercise in each of the groups was not statistically significant in both groups (p=0.399). This paper indicated that ingestion of 1 g·kg-1 body mass of carbohydrate with high or low glycemic index 2 hours before endurance exercise had limited effects on hs-CRP concentration.
