The present study was undertaken with an aim to elucidate the effects of chronic restraint stress on the metabolic variations of the glycemia, cholesterol, triglycerides and the evolution of depression. The chronic restraint stress was applied in rats Female Wistar albinos (1hour /day, 4 days / week for 5 weeks) in perforated plastic cylinders so that they can breathe. The results obtained show a reduction in the cholesterol level and increase in the triglycerides rate and glycemia, with appearance of a depressive state evaluated in the test of open Field at the batch stressed after the application of the pallet of the chronic stress.
