For investigation the effect of use of ginger, black pepper on performance of broiler chicks a total 240 one day broilers chicks were divided into 4 groups of 15 birds each and assigned to 4 treatment diets. Chicks were fed by basal diet as control diet ,2% ginger (T1), 2% black pepper (T2) and 1% ginger + 1% black pepper powders (T3).At the end of trial 4 birds form each group were slaughtered. In addition feed intake (FI), body weight gain (BW), feed Conversion ratio (FCR) were compared together. Some blood parameters such as Calcium, Phosphorus, Cholesterol and Triglyceride were determined. And they were taken for antibody titer against new castle vaccine evaluation on 22, 36 and 42 days old chicks. Data showed that use of T1, T2 and T3 increased FI significantly in comparison to control diets (p<0.05). Chicks were fed with T2 diet was higher BW among others groups. Data from this study showed that amounts of triglyceride were lower when chicks used T3 diets and cholesterol was lower in T1 group. Blood calcium decreased when chicks used T1, T2, T3 respectively and amount of Phosphorus was higher when chicks used T2 diet (p<0.05). New Castle Vaccine Antibody titer tests showed that antibody titers at 21, 35 and 42 days were significantly higher when broilers fed with T1, T2, T3 than control (p<0.05).Drumstick % was increase were broilers fed with T1,T2,T3 and Breast meat % was higher than others for T3(p<0.05).Data that showed of gizzard % was higher in the T2 and it was at the lowest in control group (p<0.05). Weight % of liver was higher in control group and for borsal.f was higher in T3 (p<0.05).In conclusion it seem that inclusion of ginger and black pepper powders in broiler chicks diet at level of 2% can be useful and have significantly effects on performance, blood biochemical and immunity parameters.