Single crystal of L-histidine doped Magnesium Sulphate (LHMS) crystal has been grown from aqueous solution by slow evaporation technique. The grown crystals were subjected to powder X-ray diffraction analysis, confirming that the crystalline nature of the crystal. The mechanical properties of the grown crystals have been studied using Vicker’s microhardness tester. The UV-visible transmittance studies show that the grown crystals have wide optical transparency in the entire visible region.