The aim of this study was to evaluate the effect of intrauterine cephaprin injection 24 hours after artificial insemination on conception rate in cows with clinical endometritis. The study was conducted on a commercial dairy farm included 700 dairy cows. In present study 150 cows with endometritis were selected. Endometritis was detected according to enlarge uterus, cervix and haze vaginal discharge in estrus. Cows were randomly divided in to three groups (50 cows each). The first group received cephapirin at the first estrus and they inseminated on the fallowing estrus. The second group received cephaprin 24 hours after insemination and the third group received oxytetracycline 24 hours after insemination.14, 16 and 11 cows, from the 1st, 2nd and3rd groups were diagnosed positively pregnant after insemination respectively. There was no significant differences between the three groups (p=0.413). Considering the insignificant differences between treatment and control groups in the case of conception rate and also decrement in interval between calving and the time of first insemination in treatment group, the application of cephaprin 24 hours after artificial insemination in cows with endometritis was suggested.
