In order to evaluate the reaction of safflower to different values of Potassium and different humidity conditions, under the use of zeolite and disuse of zeolite conditions , a factorial experiment in completely randomized block design with three replications in crop year 2011-12 at the research farm in Qazvin performed. Factors examined included two irrigations level (routine irrigation (control)and irrigation from flowering stage to the next) and four levels of potassium( 0,50, 100, 150 kg/ha) and Zeolite in two levels( 0,10 Ton/ha). Goldasht variety was used in this experiment. The results showed that grain yield was significant at 1% level probability. The maximum seed yield obtained from normal irrigation and consumption of 150 kg/ha potassium and 10 ton/ha zeolite with an average of 3921 kg/ha and the minimum yield obtained from cutting irrigation from flowering stage and disuse potassium and zeolite with an average of 601.0 kg/ha. The results of this study indicate that consumption of potassium and zeolite increased seed yield in drought stress conditions amount of 70.33 percent in proportion to disuse of them.