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Effect of Chloroxylon swietenia Dc bark extracts on STZ induced diabetic rats with special attention to its glycoprotein levels | Abstract
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Abstract

Effect of Chloroxylon swietenia Dc bark extracts on STZ induced diabetic rats with special attention to its glycoprotein levels

Author(s): B. Jayaprasad, P. S. Sharavanan and R. Sivaraj

The aim of the present study is to find out the effect of Chloroxylon swietenia Dc bark methanol (CSBMEt) and aqueous extracts (CSBAEt) on glycoprotein levels of STZ induced diabetic rats liver and kidney. The level of glycoproteins such as hexose, hexosamine, fucose and sialic acid were significantly increased in STZ induced diabetic rats. Whereas, treatment with CSBMEt, CSBAEt and glibenclamide (standard drug) for 45 days, restored these levels to near normal. The results of CSBMEt and glibenclamide were comparable. On basis of these results it can be concluded that, Chloroxylon swietenia Dc bark extracts own noteworthy protective effect on glycoprotein metabolism in addition to its antidiabetic effect.