This study examines the effect of aqueous extracts of Datura stramonium seeds on the spermiogramic parameters of West African Dwarf bucks. Plant extracts were tested for their effect on the seminal characteristics at five dose levels: 0(physiological saline solution), 0.02, 0.04, 0.06, and 0.08ml/kgBW/ animal/day subcutaneously for 10 consecutive days, using Completely randomized block design (CRBD) and the spermiogramic studies of the semen were carried out. The results of the present study showed marked variations in the spermiogramic parameters of WAD bucks, as manifested by increased (p<0.05) mass activity, mass motility, sperm concentration and improved semen output but reduced (p<0.05) semen volume and total sperm cell. Semen pH in all the animals were similar (p>0.05). The scrotal circumference in the treated bucks were statistically differed (p<0.05) from the control in the period of the study. The extract produced a remarkable effect on the spermiogramic parameters (p<0.05) and this may be as a result of the active principles present in the extract used. The results showed that the bucks can tolerate the aqueous extracts when administered. Based on the finding of the present study, aqueous extract of D. stramonium seeds contains active ingredient of pharmacological significance that if properly screened using additional solvents, pharmacologically active drugs could be obtained. The significant activity exhibited by the extract on the animals, have provided scientific justification for the ethno medicinal uses of the plant in India.
