The whole parts of the plant Ocimum sanctum have been traditionally used for curing many diseases like arthritis, asthma, bronchitis, common cold, diabetes, fever etc. Numbers of active constituents from this plant are also represented. Our present study is to carry out the Dyslipidemia of the leaf extract of Ocimum sanctum oil. Cigarette smoking is a major risk factor for cardiovascular disease, including coronary heart disease, atherosclerosis (hardening of arteries) and stroke. Starting to smoke at an early age is an even greater health risk than being heavy smoker smoking induces itself causes elevation of plasma cholesterol, Triglycerides or a low HDL levels that contributes to the development of atherosclerosis, cause may be primary (genetic) or secondary. Dyslipidemia itself causes no symptoms but can lead to symptomatic vascular diseases i.e. coronary artery disease and peripheral arterial disease. The Phytochemical studies of the leaf extracts revealed the presence of carbohydrates, tannins, alkaloids, flavonoids, steroids and glycosides in Ocimum sanctum plant. Normal mice (G-I) showed no change in lipid metabolism but experimental mice that in cigarette smoke induced (G-II & G-IV) and oil administered (G-III) mice showed changes in their lipid metabolism. Based on these results present study clearly demonstrated that Ocimum sanctum oil exerts anti lipidemic effect, for prevention of dyslipidemia it may be suggested as cardio tonic.
