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Docking Studies of few C-3 Substituted Azapteridines as Hepatitis C Virus RNA-Dependent RNA Polymerase inhibitors | Abstract
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Journal of Computational Methods in Molecular Design

Abstract

Docking Studies of few C-3 Substituted Azapteridines as Hepatitis C Virus RNA-Dependent RNA Polymerase inhibitors

Author(s): Anil M. Manikrao, Niranjan S. Mahajan, Rahul D. Jawarkar, Devidas T. Mahajan, Vijay H. Masand, Taibi. ben. Hadda

Docking studies of few C-3 Substituted Azapteridines which act as Hepatitis C Virus RNADependent RNA Polymerase inhibitor was performed by using MOE 2009. The docking studies reveal that majority of the Azapteridine derivatives interacted with Hepatitis C Virus RNADependent RNA Polymerase through hydrogen bonding as well as hydrophobic interactions. The present analysis is useful in future drug design.