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Development and validation of visible spectrophotometric method for the estimation of zaltoprofen in tablet dosage form | Abstract
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Abstract

Development and validation of visible spectrophotometric method for the estimation of zaltoprofen in tablet dosage form

Author(s): Srinivasa Rao Y., Purnima Gandi, Vara Prasada Rao K. and Hemant Kumar T.

A novel, simple, sensitive, precise and accurate visible spectrophotometric method has been developed for the estimation of Zaltoprofen in Pharmaceutical tablet dosage form. Zaltoprofen with 2, 4-dinitrophenyl hydrazine reagent (2,4 DNP) forms orange-red colored complex that exhibited maximum absorbance at 446.5 nm. The linearity dynamic response was found to be in the concentration range of 5-55 μg/ml and correlation coefficient was found to be 0.999. The results of analysis for the method have been validated statistically and by recovery studies indicate the accuracy and precision of the method. The proposed method was simple, accurate, and precise hence can be applied for the analysis of Zaltoprofen in pharmaceutical tablet dosage form.