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Development and evaluation of herbal formulation from Polyalthia longifolia, Tabernaemontana alternifolia, Benincasa hispida plant extracts | Abstract
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Abstract

Development and evaluation of herbal formulation from Polyalthia longifolia, Tabernaemontana alternifolia, Benincasa hispida plant extracts

Author(s): Gaurav M. Doshi and Bhagyashree V. Vanmali

Today’s age has anticipated the importance of herbal formulations in the treatment of various diseases comprising from major to minor ailments. The importance of these herbal development industries has immensely gained momentum due to the underlying side effects associated with allopathic medicines ranging from minor problems such as ulcerations to major life threatening problems such as growth retardation. In the present research studies the aim was to develop oral herbal tablets from Polyalthia longifolia (PL), Tabernaemontana alternifolia (TA), Benincasa hispida (BH) plant extracts and perform its evaluation as per ICH guidelines. PL and TA leaves were extracted by cold extraction at room temperature and BH fruit peels was extracted by petroleum ether using soxhlet extraction process. Wet granulation method was used for the development of oral herbal tablets. The developed herbal tablets were evaluated by paramaters such as general appearance, hardness, friability, disintegration time and dissolution profile as per ICH guidelines at different temperatures and humidity. The developed herbal tablets showed decent elegance and palatability followed by good hardness, friability, disintegration time and dissolution characteristics. Thus, article discusses and encompass the readers vision that in future local plants developed formulations could be probable prove to be equipotent with medicinal plants formulations useful for various therapeutic purposes.