The objective of this project was to determination of Safflower whole seed Organic matter (OM) degradability by nylon bags technique .Three male sheep's of Iranian Ghezel rams were used to incubating Bags . Diets containing alfalfa (60%), concentrates (40 %) and safflower whole seeds were fed twice daily during four weeks periods . Seeds were coarsely crashed and incubated for 0, 2, 4, 8, 16, 24 and 48 hours in small Dacron bags . The dates obtained from Degradability parameters of OM for water soluble fraction (a), slowly degradability fraction (b), potential degradability (a+b) and constant rate (c) were 8.3, 39.6, 0.216, 47.83 respectively. Effective degradability (r) 0.02 for OM was calculated . According to results, Safflower whole seed could use as a good source of dietary nutrient in ruminant.