In the present investigation, a series of substituted 2-(6-methoxynaphthalen-1-yl)-3-(4-phenylthiazol-2- yl)thiazolidin-4-one (5a-f)have been prepared by the condensation of N-((6-methoxynaphthalen-1-yl)methylene)-4- phenylthiazol-2-amine (4a-f) with mercaptoacetic acid in zinc chloride and ethanol. The structures of newly synthesized compounds were confirmedby IR, 1H NMR, mass and elemental analysis. All the synthesized compounds were evaluated for anti-inflammatory (in-vitro) and antimicrobial activity.
