Cyphostemma glaucophilla is used in treating malnutrition traditionally in the Igala speaking area of Kogi state of Nigeria. [18] had reported its potential in cardiovascular health and in electrolyte balance. The effects of aqueous leave extract of Cyphostemma glaucophilla on lipid profile and plasma electrolytes were evaluated in albino rats. The lipid profile was determined using standard kits obtained from Randox and electrolytes were analyzed using a flame photometer. Significant (p<0.05) lipid lowering effect of the extract was maximized at 2.0mglkg body weight. The percentage decrease in total cholesterol, triacylglycerol, low density lipoproteins and very low density lipoproteins were 20.83, 65.83, 36.33, 37.63% while the percentage maximum increase in high density lipoprotein was 51.92%. There was also significant (p<0.05) decreases in the concentrations of sodium and chloride ion by 15 and 25% respectively. However, there were significant (p<0.05) increases in the levels of potassium, calcium and zinc by 38.20, 40.50 and 43.20%. Extract had non significant (p>0.05) effect on the concentration of Hydrogen carbonate. Result has established ethno medical claim on extract in managing cardiovascular health and macro nutrient malnutrition.
