Ampelocissus latifolia (fam. Vitaceae) is climber with annual stems and fasciculated tuberous roots found in India. Traditionally people uses root in skin disease, fracture, as a tonic, for wound healing, diuretic, in eye disease, gonorrhoea, syphillis, menstrual troubles, rheumatic affection. A. latifolia contains flavonoids, saponins and reducing sugar. In present study freshly collected and dried root powder of Ampelocissus latifolia (Roxb.) was subjected to hydro alcoholic extraction. The extracts were tested for anti-inflammatory activity in carrageenan induced paw edema in rat by oral and topical application. The result found marked inhibition of inflammation in orally given and topically applied extracts. The results also suggest that hydro alcoholic extract administered orally is more effective than topically applied extract.
